![]() Except for the kidney, only a small fraction of the injected U was retained in soft tissues. ![]() Whole-body retention was 17% at 7 days, 10% at 94 days, 7.6% at 1 year, and less than 5% at 2 years PI. Up to 60% of the injected U was excreted during the first more ยป day, most of it in the urine. The uranium in the blood at 5 min PI was present as either a protein (transferrin-albumin) or a carbonate/bicarbonate complex. The concentration of U in plasma decreased rapidly, and for the first 24 h PI could be described by triphasic exponential equation with half-times of 0.92, 46, and 315 min. 3 mg/dog) in citrate buffer and sacrificed at times ranging from 1 to 726 days postinjection (PI). The distribution, retention, and excretion of /sup 233/U were measured in seven beagles injected intravenously with 2.8.
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